Jillian Van Volkenburgh is a multidisciplinary artist. Moving from painting to photography to sculpture, the subject matter dictates the medium. Her work is rooted in her experiences in the industrial corridor southeast of Chicago. She is currently focused on work based on personal transition, with themes of home, work, legacy, and death. These themes are translated into variations of both symbolic and literal imagery, ultimately creating a broad self-portrait.

In 2021, she designed and installed the Chairman Fred Hampton Gravesite Memorial in Louisiana with the permission and oversight of the Chairman Fred Hampton Estate. Work based on the memorial was included in the 2022 exhibition This Fragile, Tender Thing at Jack Shainman: The School in Kinderhook, New York.